RAW 264.7

Supplier:  CLS cell lines service, Germany

Cat no.:          400319

Amount:         1 cryovial

Organism:      Mouse

Tissue:           Ascites

Disease:        Leukemia

Age:                Adult

Gender:          Male

Celltype:         Macrophage

Growth Properties:  Adherent

Discription:      The RAW264.7 cell line was established from a preparation of macrophages of a BAB/14 mouse. Due to an infection with the Abelson-Mouse-Leukemia Virus (Ab-MLV) and an ecotropic MLV, the BAB/14 mouse had developed tumors. The macrophage-like cells will pinocytose neutral red and will phagocytose latex beads and zymosan. They are capable of antibody dependent lysis of sheep erythrocytes and tumor cell targets. LPS or PPD treatment for 2 days stimulates lysis of erythrocytes but not tumor cell targets.

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