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EastMab BioRecombinant Human Interleukin-21 (IL-21) Protein is a potent immunoregulatory cytokine that regulates T cells, B cells, natural killer (NK) cells, and antibody production. It is widely used in immunology, cancer immunotherapy, infectious disease, and autoimmune disease research.
IL-21 exerts its effects through binding to the IL-21 receptor (IL-21R), activating downstream JAK/STAT signaling pathways that regulate immune cell proliferation, differentiation, survival, and effector function. It promotes B cell maturation and antibody production, enhances CD8+ T-cell responses, supports NK cell cytotoxicity, and contributes to the development of long-term immune memory.
Because of its broad immunomodulatory activity, Recombinant Human IL-21 Protein is extensively used in studies of cancer immunotherapy, vaccine development, infectious diseases, autoimmune disorders, T-cell biology, and cytokine signaling. The recombinant protein provides a reliable and reproducible reagent for in vitro and translational research applications.
For Research Use Only (RUO. Not intended for diagnostic or therapeutic applications.)
