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Anti-HLA-DR PE-Cy5 from EXBIO Praha A.S., Czech Republik. 100 tests.
Cat-no: T8-690-T100
Size: 100 tests
Antigen: HLA-DR
Clone: L243
Format: PE-Cy™5
Reactivity: Dog, Non-human primates, Human
Excitation laser: blue (488 nm)
Store at: 2-8°C. Protect from prolonged exposure to light. Do not freeze.
HLA-DR, a major histocompatibility complex class II surface protein, is expressed on antigen-presenting cells such as macrophages, dendritic cells, and B cells. Flow cytometry experiments utilizing the HLA DR antibody have become crucial in immunology research, diagnostics, and clinical evaluations.
The Anti-HLA-DR PE-Cy™5 conjugate is a particularly powerful tool in flow cytometry due to its dual-fluorescence capability, allowing for simultaneous detection of HLA-DR and other cellular markers.
This is especially useful when analyzing complex cell populations or when phenotyping specific immune subsets.
In a typical flow cytometry experiment:
The HLA DR antibody, especially when conjugated with sophisticated tags like PE-Cy™5, allows for the identification of cells participating in the immune response. This becomes invaluable in clinical settings for various reasons:
In summary, the Anti-HLA-DR PE-Cy™5 conjugate and the HLA DR antibody are essential instruments in flow cytometry experiments, providing detailed insights into immune cell activation and regulation.
Their role in diagnosing and monitoring various diseases cements their importance in both research and clinical settings. The versatility of the HLA DR antibody, especially when combined with advanced fluorochromes like PE-Cy™5, ensures it remains a cornerstone in immunological investigations.