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EastMab BioRecombinant Human Laminin 511 E8 is a biologically active fragment of laminin-511 that supports cell adhesion, survival, proliferation, and pluripotency. It is widely used as a defined extracellular matrix substrate for human induced pluripotent stem cells (iPSCs), embryonic stem cells (ESCs), organoid culture, and regenerative medicine research.
Compared with full-length laminin or undefined matrix preparations, Laminin 511 E8 provides a highly defined and reproducible culture surface that supports long-term expansion of human pluripotent stem cells while maintaining their undifferentiated state. Its high affinity for integrins α6β1 and α3β1 promotes robust cell attachment and survival under feeder-free culture conditions.
Recombinant Human Laminin 511 E8 is extensively used in stem cell research, organoid development, tissue engineering, regenerative medicine, disease modeling, gene editing workflows, and cell therapy development. The recombinant format minimizes lot-to-lot variability and enables reproducible results in advanced cell culture applications.
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
