L-929

Supplier : CLS cell lines service ,Germany

Cat no. : 400260

Amount : 1 cryovial

Organism:      Mouse

Age:               100 days

Gender:          Male

Celltype:          Fibroblast

Growth Properties:  Adherent

Discription:  The 3T3 cell line was established from 17 to 19 days old mouse embryos. A confluent monolayer yield 40.000 cells/cm2. The cells do not adhere well on some types of glass surfaces.

History and Usage

The L929 cell line has been a cornerstone in various research domains for many decades. Originating from the tissues of a mouse, specifically from the connective tissue of a C3H/An strain mouse, L929 cells play a vital role in our understanding of cell biology and immunology.

The inception of the L929 cell line traces back to the mid-20th century, and since then, its applications have expanded widely. Given the robustness and versatility of this cell line, it became a favorite among researchers for a multitude of studies. The L929 is widely recognized for its role in the testing of the biological response of materials, often used to assess the cytotoxicity of dental materials, prosthetics, and other biomedical devices. It offers insights into how these materials interact with mammalian cells, predicting potential toxic effects.

Furthermore, L929 cells have been employed extensively in virology. They serve as a suitable host for various viruses, aiding in the cultivation, isolation, and study of these infectious agents. The cell line’s relevance is also seen in studies focusing on tumor necrosis factor (TNF) responses. Its sensitivity to TNF makes it an ideal model for evaluating the role of this cytokine in inflammation and immunity.

Recognizing the immense significance of the L929 cell line in scientific endeavors, Cell Line Service offers this cell line with the assurance of quality and authenticity. Reliable cell line providers, like Cell Line Service, understand the paramount importance of consistency in research. As the world of cellular research is intricate and demands precision, sourcing cell lines from trusted suppliers becomes imperative. Researchers and institutions have consistently turned to Cell Line Service for their requirements, knowing that the L929 cells they receive are of the highest standard.

Cell Line Service, with its dedication to quality, ensures that each batch of L929 cells undergoes rigorous quality control. This commitment ensures that researchers can place their trust in the cell lines they receive, allowing them to drive their experiments forward with confidence.

In conclusion, the L929 cell line, with its rich history and broad spectrum of applications, remains an invaluable tool in scientific research. As we navigate the complexities of cellular biology, it is essential to have trusted partners like Cell Line Service to ensure that the foundational elements of our research – the cell lines – are dependable and of the highest caliber.

 

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